- Nov 9, 2021

Cancer X CBD

In my early 20s, I developed a high blood pressure. It's not in the family and I've been athletic and fairly healthy all my life, so no one understood where it came from.

In the UK, research was started into what it could be, but nothing was found, so I was stamped as a person with hypertension. However, I refused with it and also refused to take a lot of pills, and I repeated that please find out the reason why it is so high on me (every day around ~220/180 for ~6 years)! However, my request was not achieved and walking around with such high blood pressure for such long time such a bit me from the back in the form of a stroke.

After the stroke, however, it was discovered that my hormone numbers were unusually high (ref.value ~ 300, I had ~ 900) and doctors started to suspect that the high blood pressure is due to the hormone cancer (pheochromocytoma). Adrenal cancer grows adrenaline in the body, which increases the high blood pressure. Hormone cancer / pheochromocytoma / adrenal tumor - so many different ways to call it 😁

When I started googling for the symptoms, everything came together: insane sweating, acne, high blood pressure, shortness of breath, etc. Although, yes, these symptoms are quite basic so probably a lot of people could say they might have it taking these in count 😁

However, the investigations did not reveal anything. I was told that the pheochromocytoma was insidious. And often it can only be a few mm in size, and if the machine takes a picture of the body every 5 mm, it can stay in the dark hole. Interesting, right?

So we agreed with the doctor that we will check again every six months, and as soon as it gets in the picture, it's almost an immediate operation to cut it out, and once it's out of me the high blood pressure will be gone too. Super! In the meantime, I have to take blood pressure lowerers. However, this meant that I had to take 60mg a day to keep it normal, and as soon as I forgot to take it one morning / evening, it started to rise within a few hours.

For you to understand easier, I took 25mg carvedilol and 5mg enalapril in the morning and 25mg carvedilol and 5mg amlodipin in the evening.

24.09.2021 I started consuming CBD oil. I had heard it helps with a lot of things, but didn't think to get so good results - read my previous CBD blog post!

When I had been taking CBD for almost couple of weeks, I dropped the blood pressure pills in the morning, hoping that maybe CBD also works for my high blood pressure (although I had read a lot that it only lowers it in case of stress / insomnia / anxiety, etc.). However, the indicators started to rise quite quickly, so I thought that okay, since it only lowers the pressure with the above-mentioned things, then I’ll take the tablets in again.

But then… On the morning of October 24, 2021, during my regular tablet round, I discovered that carvedilol had run out. I had also no valid prescription to go to the pharmacy and I will get an answer from the doctor only tomorrow, because it was Sunday! I thought then, okay, no worries, if it gets out of hand, then I can handle with amlocard and enarapril one day, that tomorrow everything will be back to normal again. Took only 5mg enalapril in that morning and went on with the day - measuring my blood pressure every little time.

To my surprise, however, it did not rise. In the evening, I just took 5 mg of amlocard and went to sleep. In the morning, however, the surprise was even greater when it was still only 118/84. Yes, I know because I started writing it down to see what it was doing. But I was happy and continued with just 10 milligrams a day.

A few days later I got food poisoning and I was feeling so bad that I couldn’t control blood pressure every now and then. So I sent my mother to take out carvedilol for me. Having not been well, I thought that it could not be that my pressure was normal in the current situation and I took 25mg of carvedilol and 5mg of amlocard in the evening.

Due to that, I collapsed as I began to move at night. Mom, hearing the fall, immediately jumped out of bed, and when she woke me up, I felt as if I had taken a long nap on the floor, even though it was only a few seconds. In terms of blood pressure, the machine showed ~84/32. I remember I was confused. How have I come from one extreme to another?! How is my blood pressure suddenly okay with just 10 milligrams a day, if before it started rising as soon as I forgot taking some of 60mg a day?

Again, a few days passed, I had already recovered from the food poison, and I began to think about CBD oil, that I had read how CBD can shrink cancer cells and maybe even alleviate them completely. It also reminded me that when they remove an adrenal tumor from the body, the high blood pressure is no longer there and I wouldn’t have to swallow tablets anymore.

In my head:

Pheochromocytoma -> high adrenaline -> high blood pressure -> 60mg lowerers per day -> normal blood pressure -> CBD -> decreased cancer cells -> decreased cancer cell activity -> low blood pressure -> 10mg blood pressure lowerers per day ……………

Sounds logical, doesn't it? Say more. New research began. 💡

I'll bring out some of my findings here as well. At the end of the post some links added as to what I read.

First, SO many different studies confirmed what I had heard / read. Cannabinoids have shown an anticancer potential by modulating several pathways involved in cell growth, differentiation, migration and angiogenesis.

If you've read my previous CBD blog post, you'll definitely understand the following. Cannabinoids are comprised of a group of chemical compounds found in the marijuana plant Cannabis sativa which produces more than 500 different compounds throughout its life cycle, of which more than 100 are identified as phytocannabinoids. The two major components are delta-9-tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD). Other minor components are cannabinol (CBN), tetrahydrocannabivarin (THCV) and cannabigerol (CNG). The Δ9-THC is the psychoactive cannabinoid that binds to CB1 and CB2 cannabinoid receptors identified in mammalian organisms. CBD does not have psychotropic activity, and is used to treat neurological diseases and cancer.

The literature strongly suggests a role for the endocannabinoid system in the pathogenesis of cancer. It is evident that cannabinoids target key signaling pathways affecting all the hallmarks of cancer.

It has also been found, for example, that despite modern modalities of chemotherapy and irradiation treatment, glioblastoma remains one of the most malignant cancer types. Several phytochemicals exhibit important properties against this form of cancer, including the cannabinoids delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) from Cannabis sativa. Once inside, the cannabinoids interfere with specific biochemical pathways, promote tumour cells’ growth arrest, inhibit their invasion and cause cell death.

In over 20 animal studies, CBD/THC was found to drastically decrease the size of and even eliminate glioblastoma. In addition, some clinical trials and reports of these two cannabinoids show varying anti-glioblastoma activity in combination with other therapies.

However, wider clinical application of these preparations is hindered due to the psychotropic effects of THC. This often limits the clinical usage of THC and CBD mixtures in glioblastoma patients as many will already present with adverse neuropsychiatric symptoms, including impaired cognition.

Also the cannabinoids action in gastrointestinal cancers has been demonstrated in vitro and in vivo, indicating their antiproliferative, proapoptotic, and antimetastatic properties. Of note, it has been demonstrated that endogenous cannabinoid agonists, such as AEA and its metabolic-stable analogous, Meth-AEA, diminished the volume and the density of gastric carcinomas cells, inducing apoptosis and necrosis, respectively.

As much as I read, good results have been received for a huge variety of cancers. To name a few: leukemia, lymphoma, breast cancer, brain tumor, etc.

In a cancer context, cannabinoids have been shown to alleviate nausea and vomit induced by chemotherapy. Cannabinoids also inhibit pain. Other potential palliative effects of cannabinoids in oncology include appetite stimulation and attenuation of wasting.

Both older and more recent studies have provided medical evidence revealing both THC and CBD provide anti-cancer properties — and they don’t harm healthy, normal cells while they fight cancer cells. Other traditional treatments, not only harm cancer cells but also healthy cells.

Cannabinoids like CBD, THC, CBC, CBG, CBDa and THCa all benefit people who live with cancer. CBD alone is known to lower inflammation, relieve pain and reduce anxiety without creating the “high” feeling THC does.

On my case, before making this post, I did a quick search of the blood pressure lowerers I took/am taking, what exactly helps with what and again… I was amazed by what I found. Carvedilol is a beta blocker, meaning it stops the hormone adrenaline from working within the heart and blood vessels.

Now I need to get rid of enalapril and amlodipine. Yet to figure that out!

In summary, although this tumor in me has not been detected on pictures, it sounds like the only logical explanation for my blood pressure drop is that because as far as I could find and read, all studies of 'high blood pressure with CBD' have been positive in stressful situations, insomnia, anxiety and nothing else. 🤷‍♀️

This was my research on the effects of CBD oil on tumors. I hope this helps!

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Here's a little literature to read more and search for yourself